Description
Product Characteristics:
Aliases: Histone-lysine N-methyltransferase 2B antibody, HRX2 antibody, KIAA0304 gene product antibody, KMT2B antibody, KMT2B_HUMAN antibody, Likely ortholog of mouse WW domain binding protein 7 antibody, Lysine N-methyltransferase 2B antibody, mixed lineage leukemia 4 antibody, Mixed lineage leukemia gene homolog 2 protein antibody, MLL2 antibody, myeloid lymphoid leukemia 4 antibody, Myeloid lymphoid or mixed lineage leukemia protein 4 antibody, Myeloid/lymphoid or mixed-lineage leukemia protein 4 antibody, Trithorax homolog 2 antibody, trithorax homologue 2 antibody, TRX2 antibody, WBP-7 antibody, WBP7 antibody, WW domain-binding protein 7 antibody
Target Information: This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known. [provided by RefSeq, Jul 2008]